hello All, I am a 40 year Indian male , has undergone kidney tx two years ago. Last week my TAC was at 12.3 and Creatinine was 1.5 at prograf 0.5 BD . My doc reduced pangraf to 0.5 and 0.25 respectively. 0.25 in morning and 0.5 in evening. that reduced TAC to 4.95 and Creatinine to 1.5 in four days.I am having quite warm palm and feet since last few days and feeling heat in body. Can any body suggest what could be the reason of these fluctuation.