Replies to This Discussion

Permalink Reply by Mohan on May 24, 2012 at 11:39pm

I have of late, but never realized that it was due to Myfortic?  I have been on 720 mg twice a day since a bout with liver rejection 6 months ago.  I don't have sleep problems every night, but there have been weeks where sleep has come with great difficulty.

Permalink Reply by Roxeal on May 29, 2012 at 7:36pm

I find some hearty exercise can help, as can either taking compazine pills, dyphenhydramine, or even some Tylenol.  I also have to be sure my BP is not high, and my hormones are working.  Anemia can be caused by  high doses and also causes sleep issues.  Hope you find some help with it.   As soon as I had my transplant, I began to be up till 1am every single night, awful.  It is a bit better now, but I really had to focus on getting out of that trap.

Permalink Reply by Sheila Boyd George on May 29, 2012 at 7:57pm

I called the doctor, he did not feel the Myfortic was the cause.  Suggested I try Tylenol PM.  Anyway, the pattern of not sleeping has broken, and now I have trouble staying awake, which is my norm.  Maybe I just needed to get used to the increased dose of the Myfortic.  Surprisingly when I was on the dose right after transplant I did not have this problem.  The dose has been lowered due to low WBC and CMV.  Anyway, I am just glad to be able to sleep again!!  Thanks for your replies! :o) 

Permalink Reply by Richard Lopez on July 13, 2012 at 6:43pm

I definitely have had sleep issues since my kidney transplant back in October of 2008.  I think the Myfortic combined with Prograf have been part of the issue.  Ever since I have been taking Ambien 10 mg to get to sleep but sometimes that doesn't help.  I have found that Alteril (all natural over the counter sleep aid) in conjunction with 5-10 mg Ambien helps when I really need to sleep but can be a bit too much at times so I just try to stick to the Ambien or the Alteril.  Another thing that I had tried is a sub-lingual melatonin right before you go to bed.  Be very cautious when tinkering with your meds though.  I don't mess too much with my immunosuppressants but some of the others you can switch around a bit, etc.  For example, my primary care physician recommended that I take my blood pressure medications before going to bed as opposed to taking them in the morning.  Also any anti-depressants could possibly help to take later at night as well.

Permalink Reply by Marina on August 21, 2012 at 10:21pm

I  take  720mg  in  AM  and  360mg  in  PM  but  LUCKILY  don't have    that  problem.

I  took  720mg  2x/day  the  first  3months post  TX,  I slept  slept and then I  slept  some  more.

I  count my  blessings  everyday!!

Permalink Reply by Janelle on December 9, 2012 at 6:53pm

I had issues with sleeplessness and Myfortic starting right after my transplant. And whenever my counts change and we change the dosage it tends to pop up again. Currently I am on 360 mg a day, and I take it in one pill, so I put it in my am meds, which has helped significantly!